DEPARTMENT.FACULTY

photo
Dr. Samima Khatun
  • DEPARTMENT_STAFF.QUALIFICATION

    Ph.D (Biophysical Chemistry)

  • DEPARTMENT_STAFF.DESIGNATION

    Guest Faculty

  • DEPARTMENT_STAFF.THRUST_AREA

    Protein-ligand Interaction by using Spectroscopic, ITC and computational techniques, Protein-protein binding mechanism

  • DEPARTMENT_STAFF.ADDRESS

    Nischintapur, Khandaghosh, Dist-Purba Bardhaman, W.B

  • DEPARTMENT_STAFF.MOBILE

    7417664535

  • DEPARTMENT_STAFF.EMAIL

    ahmedsamima7@gmail.com

  • DEPARTMENT_STAFF.TIME_TABLE

    Time Table 2021-22 session

DEPARTMENT_STAFF.COMPLETE_CV

 

Dr. Samima Khatun joined the Department of Chemistry, AMU as Assistant Professor (contractual) in July 2019. Prior to joining the department she worked with Dr. Pannuru Venkatesu as Research Associate under CSIR Project in the Department of Chemistry, University of Delhi. She was awarded Nature Travel Grant” from Nature Communications Chemistry in 2019 and  D.S. Kothari Post-doctoral Fellowship in  2021. She defended her Ph.D under the supervision of Prof. Riyazuddeen on the topic “Thermodynamic and spectroscopic studies on interactions in protein ligand systems” in 2018. She has published various research papers in International Journals of repute of high impact factor such as New Journal of Chemistry (RSC), Journal of Molecular Liquids, Journal of Biomolecular Structure and Dynamics, Journal of Chemical Thermodynamics, Journal of Thermal Analysis and Calorimetry.

 

Her research area is:  Interaction study of protein-drug and protein-protein systems by using spectroscopic (UV-visible, Fluorescence, CD, FTIR, FRET), calorimetric (ITC) and computational (molecular docking and MD Simulation) techniques to elucidate binding affinity, binding mechanism,  conformational alteration, binding site, and amino acid residues involved in the binding process. She also works on enzyme kinetics and denaturation (both thermal and chemical induced denaturation) study to detect the effect of drug interaction on protein structure and dynamics.

 

 

  1. Samima Khatun , Riyazuddeen, Shama Yasmeen, Unraveling the thermodynamics, enzyme activity and denaturation studies of Triprolidine hydrochloride binding with model transport protein, Journal of Molecular Liquids 337 (2021) 116569
  2. Samima Khatun, Anamika Sindhu, Pannuru Venkatesu, Can Stem Bromelain, a Pineapple Waste Product, Used as Drug Alternate? A Mechanistic Insight into ProteinProtein Interactions, New J. Chem (RSC) 44 (2020) 19450.
  3. Samima Khatun, Riyazuddeen, A multiparametric in-vitro binding analysis of bovine serum albumin toward interaction with sulindac and chlorpromazine through spectroscopy, calorimetric and computational approaches, J. Mol. Liq. (2020), DOI: 10.1016/j.molliq
  4. Samima Khatun, Riyazuddeen, A. Kumar, N. Subbarao, Calorimetric, computational and denaturation studies on exploring the binding mechanism of tetramethylpyrazine with human serum albumin, J. Chem. Thermodyn. 140 (2020) 105915.
  5. Samima Khatun, Riyazuddeen, G. Rabbani, A comparative biophysical and in-silico studies on the interactions of ticlopidine hydrochloride with two serum albumins, J. Chem. Thermodyn. 131 (2019) 9-20.
  6. Samima Khatun, Riyazuddeen*, F.A. Qais, Characterization of the binding of triprolidine hydrochloride to hen egg white lysozyme by multi-spectroscopic and molecular docking techniques, J. Mol. Liq. 269 (2018) 521-528.
  7. Samima Khatun, Riyazuddeen, A comprehensive calorimetric, spectroscopic, and molecular docking investigation to probe the interaction of colchicine with HEWL, J. Therm. Anal. Calorim. 136 (2019) 1757-1767.
  8. Samima Khatun, Riyazuddeen*, Probing of the binding profile of anti-hypertensive drug, captopril with bovine serum albumin: A detailed calorimetric, spectroscopic and molecular docking studies, J. Chem. Thermodyn. 126 (2018) 43-53.
  9. Samima Khatun, Riyazuddeen, S. Yasmeen, A. Kumar, N. Subbarao, Calorimetric, spectroscopic and molecular modelling insight into the interaction of gallic acid with bovine serum albumin, J. Chem. Thermodyn. 122 (2018) 85-94.
  10. Samima Khatun, Riyazuddeen, Interaction of colchicine with BSA: spectroscopic, calorimetric and molecular modeling approaches, J. Biomol. Struct. Dyn. 36 (2018) 3122- 3129
LISTDownloadUPLOADED DATE
unit 3(b) Thermochemistry
19/04/2020
unit 3(a) Thermodynamics
19/04/2020
unit 2 catalysis
19/04/2020
unit 1 chemical kinetics
19/04/2020
Assignment I
02/05/2020
Assignment I
08/05/2020
Assignment II
12/05/2020
unit 4 (2nd law of thermodynamics)
27/05/2020
Assignment III
02/06/2020