DEPARTMENT.FACULTY
- DEPARTMENT_STAFF.QUALIFICATION
Ph.D.
- DEPARTMENT_STAFF.DESIGNATION
Assistant Professor (Contractual)
- DEPARTMENT_STAFF.THRUST_AREA
Medicinal Inorganic Chem, Synthesis of inorganic metal complexes, Protein Biochemistry (inhibition of amyloid aggregation), Sensors, drug delivery
- DEPARTMENT_STAFF.ADDRESS
Moh. Nazar Khail, Saraitareen, Sambhal (U.P.)
- DEPARTMENT_STAFF.MOBILE
7037041900
- DEPARTMENT_STAFF.EMAIL
huzaifayasirkhan@gmail.com
- DEPARTMENT_STAFF.TIME_TABLE
Time Table 2024 Even SEMTime table 2024 odd semTime Table 2024Time Table 2023 Odd SEM
Dr. Huzaifa Yasir Khan received his B.Sc (Hons.) degree and Master’s degree in Chemistry from Department of Chemistry, Aligarh Muslim University, India. He was awarded prestigious DST INSPIRE Scholarship for five years during his undergraduate and master’s programme. He completed his Ph.D. degree in 2021 under the supervision of Prof. Farukh Arjmand, Department of Chemistry, AMU on the topic “Synthesis and Characterization of tailored metal-based potential antitumor chemotherapeutic drug candidates” with ‘DST INSPIRE Fellowship’ (DST-JRF and SRF). Following his PhD, Dr Huzaifa Y. Khan worked as ICMR Research Associate at Interdisciplinary Biotechnology unit, Aligarh Muslim University, Aligarh where he used different spectroscopic techniques to determine inhibitory potential of novel transition metal complexes against the aggregation of amyloid protein. The aggregation of amyloid protein is one of the hallmark of neurodegenerative disorder like Alzheimer. Millions of people worldwide get affected with neurodegenerative disorders like Alzheimer’s and Parkinson’s diseases. Currently, we do not have an effective way to treat these diseases. Small molecule drug based therapies have been developed to some extent but these drugs are highly non-specific and toxic to healthy tissues as well. Conjugating small molecule drugs with nanoparticles/peptides that site-specifically targets diseased tissues offers a very promising strategy to overcome these challenges. His primary research interest is mainly focused on designing metal complexes to target various disease. His long term research interest lies in to test the efficacy of these therapeutic conjugates on animal model systems bearing amyloid aggregates. Dr Huzaifa has successfully completed CSIR skill development programme at NCL pune on DFT and delivered his oral/poster presentation at IIT madras, BHU, varanasi, IISER pune and Indian Council of Chemists and awarded Young scientist for the best oral presentation. (https://www.amu.ac.in/news/2023/1/02/amu-faculty-conferred-with-prof-wu-malik-memorial-award). He has published several research articles in international journal of repute with good impact factors. He also co-authored a book by Springer Nature entitled Advances and prospectus of 3d metal based drug candidates. https://www.amu.ac.in/news/2024/05/22/amu-vc-releases-a-book-on-anticancer-drug-candidates.
- Book co-authored
Advances and Prospects of 3d Metal-Based Anticancer Drug Candidates.
- Advances of metallodrug-amyloid ? aggregation inhibitors for therapeutic intervention in neurodegenerative diseases: Evaluation of their mechanistic insights and neurotoxicity
Coord. Chem. Rev. 501 (2024) 215580. https://doi.org/10.1016/j.ccr.2023.215580
- Metal complexes of NSAIDs as potent anti-tumor chemotherapeutics: Mechanistic insights into cytotoxic activity via multiple pathways primarily by inhibition of COX–1 and COX–2 enzymes Coordination Chemistry Review, 453, 2022, 214316. (I.F. 20.6)
- Structural insights into interactions of new polymeric (?–oxo) bridged Cu(II) complexes of taurine with yeast tRNA by spectroscopic and computational approaches and its application towards chemoresistant cancer lines Siffeen Zehra, Huzaifa Yasir Khan, Thierry Roisnel, Sartaj Tabassum, Farukh Arjmand,Int. J. Biol. Macromol. 2023, 240, 124429. (I.F. 8.025)
- Synthesis and structural elucidation of a unique turn-off fluorescent sensor based on oxo-bridged tin (IV) cluster for selective detection of dopamine in biological fluids
R. Kouser, Huzaifa Yasir Khan, F. Arjmand, S. Tabassum, Spectrochimica Acta Part A, https://doi.org/10.1016/j.saa.2023.123152.