DEPARTMENT.FACULTY
- DEPARTMENT_STAFF.QUALIFICATION
Ph.D.
- DEPARTMENT_STAFF.DESIGNATION
Professor
- DEPARTMENT_STAFF.THRUST_AREA
Protein and nucleic acid immunology
- DEPARTMENT_STAFF.ADDRESS
SambhaliGate, Moradabad, 244001
- DEPARTMENT_STAFF.MOBILE
9412273580
- DEPARTMENT_STAFF.EMAIL
asifali_amu@rediffmail.com
Dr. Asif Ali did M.Phil and Ph.D in 1981 and 1984, respectively, in Biochemistry from the Faculty of Medicine, A.M.U. He has been involved in teaching for 32 years. He was appointed as Lecturer in 1988, Reader in 1994 and Professor in 2003. He has completed 2 terms as Chairman of the Department of Biochemistry. Presently, working as the Coordinator of IBRC and Chairman cum Scientist in charge of Central Animal house of J. N. Medical College. Dr. Asif Ali has been actively engaged in research for the past 40 years. His major field of research interest is in protein and nucleic acid immunology and the role of modified proteins and nucleic acids in various diseases. He has supervised 2 M.Phil and 10 Ph.D candidates, and successfully guided 9 MD students as Supervisor and 13 MD students as Co-Supervisor. He has published two book chapter, 85 research papers in international and 11 in national journals of high repute. He has presented 115 research papers in various scientific conferences. He has successfully completed five research projects as Principal Investigator. Successfully organized an International E-conference on Brain Tumors and Stem Cells as Therapeutic Targets-2021 at Interdisciplinary Brain Research Center, Faculty of Medicine, Aligarh Muslim University, Aligarh on 4th February 2021 and World Neurocongress-2017, an International Conference on Neurogenomics and stem cell therapy, at Interdisciplinary Brain Research Center, Faculty of Medicine, Aligarh Muslim University, Aligarh on 9-10 December, 2017.
- Publication
1. Akhtar, F., Khan, A. U., Misba, L., Akhtar, K., and Ali, A. (2021) Antimicrobial and antibio film photo dynamic therapy against vancomycin resistant Staphylococcus aureus (VRSA) inducedinfection in vitro and in vivo. European Journal of Pharmaceuticals and Biopharmaceutics. 160, 65-76. (Impact. Factor.: 5.57)
2. Akhtar, F., Khan, A. U., qazi, B., Guru, S., Mishra, P., Akhtar, K., and Ali, A. (2021) Toluidine Blue conjugated gold–silver nano-shells mediated photodynamic therapy against diabetic foot ulcer: A nano phototheranostic approach against multi-drug resistant infections. (Under review scientific report)
3. Mustafa, M., Ali, A., Siddiqui, S. A., Mir, A. R., Kausar, T., Naeem, S., Abidi, M., and Habib, S. (2021) Biophysical Characterization of Structural and Conformational changes in Methylmethane Sulfonate Modified DNA leading to the Frizzled Backbone Structure and Strand Breaks in DNA. Journal of Biomolecular Structure and Dynamics. (2021) Mar 15:1-14. Doi: 10.1080/07391102.2021.1899051.Epub ahead of print. PMID: 33719847 (Impact.Factor 3.5)
4. Warsi, M. S., Habib, S., Talha, M., Mir, A. R., Alam, K., Ali, A., and Moinuddin. Characterization of human serum albumin modified by hair dye component, 4-chloro-1,2-phenylenediamine: Role in protein aggregation, redox biology and cytotoxicity, Journal of Molecular Liquids, Volume 331 1 June 2021, 115731(Impact factor: 5.06)
5. Rizwee, M. M., Abidi, M., Habib, S., Mir, A. R., Ali, A., and Uddin, M. (2021). Characterization of Glyoxal Modified LDL: Role in the Generation of Circulating Autoantibodies in Type 2 Diabetes Mellitus and Coronary Artery Disease. Current drugtargets,10.2174/1389450122666210114123959. Advance online publication. https://doi.org/10.2174/1389450122666210114123959. (Impact factor:2.6)
6. Asha, K.S., Habib,S., Moinuddin, Siddiqui,S.A. and Ali,A.(2021)calf Thymus DNA Exposed to Quinacrine at Physiological Temperatures and pH Acquires Immunogenicity: A Threat for Long Term Quinacrine Therapy; Indian Journal of Clinical Biochemistry, (In press)
7. Habib S., and Ali, A (2020). Increasing Use of Hair Dye and Associated Genotoxicity Needs to be Probed. Ind J Clin Biochem .https://doi.org/10.1007/s12291-020-00871-z(Impact factor: 1.9)
8. Tantry, I. Q., Ali, A. and Mahmood, R. (2021) Hypochlorous acid decreases power, inhabits plasma memberane redox system and pathways of glucose metabolism in human red blood cells; Toxicology research10,159-168 (Impact factor. 2.283)
9. Waris, S., Patel, A., Ali, A., and Mahmood, R. (2020) Acetaldehyde-induced oxidative modifications and morphological changes in isolated human erythrocytes: an in vitro study. doi:10.1007/s11356-020-08044-4. Environmental Science and Pollution Research, 27(14), 16268-16281. (Impact Factor:2.914)
10. Ahmad, P., Tantry, I. Q., Ali, A., Siddiqui, S. A., Rehman, S., Waris, S. and Jairajpuri, M. A. (2020) Structural alteration in hypochlorous acid modified antithrombin indicates generation ofneo-epitopes. Archives of Biochemistry and Biophysics. 685,108332(ImpactFactor:3.559).
11. Abidi, M., Mir, A. R., Khan, F., Ali, A. and Moinuddin (2020) Glycoxidation of LDL generates cytotoxic adducts and elicits humoral response in diabetes type 2. Glycobiology. (ImpactFactor:3.664)
12. Habib, S. and Ali, A. (2020) Increasing use of hair dye and associated genotoxicity needs to be probed. DOI 10.1007/s12291-020-00871-z. Indian Journal of Clinical Biochemistry, 35(2), 133-134.
13. Anis, E., Zafeer, M. F., Firdaus, F., Islam, S., Khan, A. A., Ali, A. and Hossain, M. M. (2019) Ferulic acid reinstates mitochondrial dynamics through PGC1? expression modulation in 6-Hydroxydopamine lesioned rats. doi:10.1002/ptr.6523. Phytotherapy Research, 34, 214-226 (ImpactFactor: 3.766)
14. Waris, S., Habib, S., Khan, S., Kausar, T., Nayeem, S. M., Siddiqui, S. A., Moinuddin and Ali, A.,
(2019) Molecular docking explores heightened immunogenicity and structural dynamics of acetaldehyde human IgG adduct. IUBMB life, 71(10),1522-1536 (ImpactFactor: 3.236)
15. Mariyath, M., Shahi, M. H., Tayyab, M., Farheen, S., Khanam, N., Tabassum, S. and Ali, A. (2019) Cadmium induced neurodegeneration and activation of non-canonical Shh cell signaling pathway in rat cerebellum. Journal of Biochemical and Molecular Toxicology, 33(4), e22274 (ImpactFactor: 1.837)
16. Firdaus, F., Zafeer, M. F., Anis, E., Ahmad, M., Hossain, M. M., Ali, A. and Afzal, M. (2019) Evaluation of phyto-medicinal efficacy of thymoquinone against Arsenic induced mitochondrialdysfunction and cytotoxicity in SH-SY5Y cells. Phytomedicine, 54, 224-230. (Impact Factor:4.180)
17. Waris, S., Habib, S., Tantry, I. Q., Khan, R., Mahmood, R. and Ali, A. (2018) Acetaldehyde-induced structural and conformational alterations in human immunoglobulin G: A physicochemical and multi-spectroscopic study. International Journal of Biological Macromolecules,113,701-710. (Impact Factor: 4.784)
18. Islam, S., Mir, A. R., Khan, F., Zaman, M.,Ali, A., and Moinuddin (2018) Structural and immunological characterization of hydroxyl radical modified human IgG: Clinical correlation inrheumatoidarthritis.SpectrochimActaAMolBiomolSpectrosc.194,194-201. (ImpactFactor:2.931)
19. Abidi, M., Khan, M. S., Ahmad, S., Kausar, T., Nayeem, S. M., Islam, S., Ali, A., Alam, K. and Moinuddin (2018). Biophysical and biochemical studies on glycoxidatively modified human low-density lipoprotein. Archives of Biochemistry and Biophysics, 645, 87-99 (Impact Factor:3.559).
20. Mariyath, M., Shahi, M. H., Farheen, S., Tayyab, M., Khanam, N. and Ali, A. (2018) Novel homeodomain transcription factor Nkx2.2 in the brain tumor development. Current Cancer drug targets. doi: 10.2174/1568009618666180102111539. (Impact Factor:2.626)