Biochemical Genetics, Disease Biology, Hepatology, Proteomics
Dr. Riaz Ahmad obtained his M.Sc. Zoology with specialization in Genetics, M.Phil and Ph.D. from the Department of Zoology, Aligarh Muslim University, Aligarh. Then he was awarded Young Scientist Project from Department of Science & Technology, Ministry of Science & Technology and subsequently DS Kothari Fellowship from the University Grants Commission to pursue Post-Doctoral Research.
The mapping of disease pathways is a vigorous affair which includes conglomeration of numerous biomarkers, transcription factors and molecules that orchestrate the signaling and form a nexus of cascades. The research on the discovery of liver proteome is targeted to determine possible fibrotic pathways and some novel biomarkers for early diagnosis of the disease. The work encompasses comprehensive and in-depth research analyzing distinct factors of abatement and instigation of hepatic fibrosis which are evidently most significant in nature. The reason of their significance being the definite exploration of path that leads to efficacy of drug development against hepatic fibrosis. These studies delineate probable ameliorative pathways and emphasize anti-fibrotic property and their use as a potential therapeutics against hepatic fibrosis.
The work has been published in journals of repute such as NATURE-Scientific Reports, J. Func. Foods, Int. J. Biol. Macromol., Food Chem., Comp. Biochem. Physiol. (B)-Biochem & Mol Biol, Chemico-Biol. Interact., Ecotox. Environ. Safety, J. Food Biochem., Environ. Toxicol. Pharmacol., Cell. Signalling, J. Trace Elem. in Med & Biol., Int. J. Food Prop., Protein & Peptide Lett. etc. Total citations are around 982 with H-index of 16 and i10 value 27 (Source: google scholar).
Human Resource Generated:
PG Research Theses: 14
Recognition and Awards:
Young Scientist Fellowship (Deptt. of Science & Technology, Govt. of India)
Young Scientist Award (Council of Science & Technology, Govt. of Uttar Pradesh)
Shakuntala Amir Chand Award (Indian Council of Medical Research, Govt. of India)
Teachers Excellence Award (Confederation of Educational Excellence, India)
BOYSCAST Fellowship to pursue research at USA (Deptt. of Science & Technology, Govt. of India)
S.N. Nahar Distinguished Teacher of the Year Award (Department of Zoology, AMU Aligarh)
Sir Syed Innovation Award: Young Researcher of the Year-Science stream (Aligarh Muslim University, Aligarh)
Research Projects from UGC, CST (UP) and DST have also been run in capacity of Principal Investigator/Co-investigator.
H. Husain, U. Latief, R. Ahmad. 2018. Pomegranate action in curbing the incidence of liver injury triggered by Diethylnitrosamine by declining oxidative stress via Nrf2 and NFkB regulation. NATURE-Scientific Reports.8: 8606 (IF = 4.122)
U. Latief, H. Husain, R. Ahmad. 2018. β-Carotene supplementation ameliorates experimental liver fibrogenesis via restoring antioxidant status and hepatic stellate cells activity. Journal of Functional Foods. 49: 168-180. (IF = 3.767)
A. Ahmad, R. Ahmad. 2018. Proteomic approach to identify molecular signature during experimental hepatic fibrosis and Resveratrol supplementation. International Journal of Biological Macromolecules.119: 1218-1227. (IF = 3.929)
H. Husain, R. Ahmad, A. Khan, Inamuddin, A.M. Asiri, 2018. Proteomic-genomic adjustments and their confluence for elucidation of pathways and networks during liver fibrosis, Int. J. Biological Macromol. 111: 379-392. . (IF = 3.929)
D. Mukherjee, R. Ahmad. 2018. Resveratrol attenuates Nitrosodiethylamine-induced liver injury in anti inflammatory manner via regulating cyclooxygenase-2. Journal of Food Biochemistry. e12594. (IF = 1.552)
A. Ahmad, R. Ahmad. 2017. In-gel detection of esterase-like albumin activity: Characterization of esterase-free sera albumin and its putative role as non-invasive biomarker of hepatic fibrosis. Arabian Journal of Chemistry. 10 (5): 673-682. (IF=4.008)
- R. Saleem, R. Ahmad. 2016. Effect of low frequency ultrasonication on biochemical and structural properties of chicken actomyosin. Food Chemistry.205: 43-51. (IF=4.879)
- A. Ahmad, R. Ahmad. 2014. Resveratrol mitigate structural changes and hepatic stellate cell activation in N′-Nitrosodimethylamine-induced liver fibrosis via restraining oxidative damage. Chemico-Biological Interactions. 221: 1–12. (IF=3.308)
- Ahmad, N. Afroz, U.D. Gupta, R. Ahmad. 2014. Vitamin B12 supplement alleviates N′-nitrosodimethylamine-induced hepatic fibrosis in rats. Pharmaceutical Biology, 2014; 52(4): 516–523. (IF=1.24)
- R. Ahmad, A. Hasnain. 2013. Peptide mapping of polymorphic myosin heavy chain isoforms in different muscle types of some freshwater teleosts. Fish Physiology and Biochemistry. 39: 721-731. (IF=1.67)
- R. Ahmad, S. Ahmed, N.U. Khan, A. Hasnain. 2009. Operculina turpethum attenuates N-Nitrosodimethylamine induced toxic liver injury and clastogenicity in rats. Chemico-Biological Interactions, 181: 145-153. (IF=3.308)
- R. Ahmad, A. V. Khan, M. F. Siddiqui, A. Hasnain. 2008. Effects of an aqueous extract of Croton bonplandianum Baill in rats. Environmental Toxicology and Pharmacology. 26:336-41.(IF=2.13)
M.F. Siddiqui, R. Ahmad, W. Ahmad and A. Hasnain. 2006. Micronuclei induction and chromosomal damage by chloroacetic acid and chlorobenzene in Rattus norvegicus. Ecotoxicology and Environmental Safety. 65(2): 159-164. (IF=4.00)
- R. Ahmad and A. Hasnain. 2005. Ontogenetic changes and developmental adjustments in lactate dehydrogenase isozymes of an obligate air-breathing fish Channa punctatus during deprivation of air access. Comparative Biochemistry and Physiology-B (Biochemistry and Molecular Biology). 140: 271-278. (IF=1.875)